The adrenal glands are located above the kidneys. The adrenal glands are made up of an outer portion, called the adrenal cortex and an inner portion, called the adrenal medulla. The cortex is responsible for making and releasing glucocorticoids and mineralocorticoids, also known as corticosteroids; and a small amount of androgenic sex hormones. Glucocorticoids such as cortisol, can affect body metabolism, suppress inflammation and help the body withstand stress. Mineralcorticoids maintain water and electrolyte balances. Derivatives of adrenal androgens, such as anabolic steroids, promote the development of muscle mass and masculine characteristics. The adrenal medulla secretes epinephrine and norepinephrine, two hormones that are released in response to stress or to facilitate the “fight-or-flight” response.